GB & BILIARY US

موضوع: رد: GB & BILIARY US الجمعة يونيو 28, 2024 6:16 pm

Gallbladder with sludge and thickened anterior wall; Possible small gallstones; Dilated common bile duct; Pericholecystic fluid; Hepatic cyst; Additional split-screen image: Abdominal CT

موضوع: رد: GB & BILIARY US الجمعة يونيو 28, 2024 6:34 pm

Large gallstone in the fundus of the gallbladder; Small gallstone in the neck of the gallbladder; Thickened gallbladder wall concerning for cholecystitis; Right renal cyst

موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 7:27 pm

The Gallbladder

Normal Anatomy

The normal anatomy of the gallbladder, biliary tract, and surrounding organs is presented in Fig. 17.1 . The gallbladder is connected via the cystic duct to the common hepatic duct, forming the common bile duct (CBD) that drains into the duodenum through the head of the pancreas. In most situations, the hepatic artery lies between the CBD and the more posteriorly located portal vein.

Ultrasound Techniques/Findings

Imaging of the gallbladder is performed using a low-frequency transducer, such as a curved array (typically 3–6 MHz frequency). It is best to visualize the gallbladder and CBD in a parasagittal, as well as transverse plane, in real time. Patients are often imaged in a supine position; however, turning the patient in a lateral decubitus or right anterior oblique position may improve visualization. Occasionally, placement of the probe in other positions, such as intercostal or through the right flank, may be helpful for gallbladder visualization. Careful and deliberate interrogation of the entire gallbladder is imperative, as stones may be impacted in the gallbladder neck or pass through the cystic duct into the CBD and cause biliary ductal obstruction. The examiner may find a sonographic Murphy’s sign to be useful. A simple test is performed by placing the probe over the gallbladder to elicit pain. We find that placing the probe in different positions may be best to localize the true site of the pain. Thus probe pressure to the right of the gallbladder, over the gallbladder, and then over the mid-epigastric region may be used to best identify the true site of pain. A sonographic Murphy’s sign is defined as the presence of maximum tenderness elicited by direct probe pressure over the sonographically located gallbladder. If analgesics have been administered, a Murphy’s sign may be more difficult to elicit. On ultrasound we are evaluating the gallbladder primarily for stones, signs of inflammation of the gallbladder, and/or biliary obstruction. If the extrahepatic biliary ductal system appears dilated, then scanning through the liver as well as the head of the pancreas to evaluate the extrahepatic biliary system is important. It is important to document potential etiologies of biliary ductal obstruction such as choledocholithiasis and/or distal mass within the pancreas. When there is biliary ductal obstruction but no identifiable etiology on ultrasound, a computed tomography (CT) scan of the abdomen should be performed. Magnetic resonance imaging (MRI) may be useful to better identify etiologies of biliary obstruction such as choledocholithiasis.

Cholelithiasis and Mimics

Cholelithiasis

The principal imaging features that distinguish gallstones are mobility, echogenic focus, and acoustic shadowing ( Fig. 17.2 ). Multiple studies have shown sensitivities of ultrasound of approximately 95%, with even higher positive and negative predictive values. Gallstones may also demonstrate a “twinkle” artifact on color Doppler imaging ( Fig. 17.3 ). When an echogenic focus is identified in the gallbladder, first shadowing should be confirmed. This is followed by repositioning the patient to demonstrate stone mobility. This can include having the patient upright or standing. Stones lodged in the cystic duct may not move. Careful attention to surrounding structures is important, so as not to confuse an echogenic bowel (which can create a “dirty shadow”) with gallstones ( Fig. 17.4 ). This artifact can be differentiated from stones by scanning the patient in different positions and noting that the bowel is not within the gallbladder fossa, as well as noting peristalsis within the bowel

Scanning in different planes or obliquely may be necessary to separate adjacent bowel from the gallbladder (see Fig. 17.4 ). A Refraction artifact, which is a mildly echogenic area in the region of the neck of the gallbladder that produces acoustic shadowing, can also be confused for gallstones. This edge artifact is due to refraction or from the multiple small valves of Heister within the cystic duct. Other nonmobile echogenicities within the gallbladder, which may be confused with cholelithiasis, are listed in Table 17.1.
TABLE 17.1
Nonmobile Echogenicities in the Gallbladder That May Shadow
    Stone lodged in the gallbladder neck
    Stone adherent to gallbladder wall
    Gallbladder fold
    Intramural gas secondary to emphysematous cholecystitis
    Adenomyomatosis with stone in Rokitansky–Aschoff sinus
The gallbladder is best examined when the patient is fasting. In emergent situations, the patient may not always be adequately prepped. Thus when the patient is not fasting, the gallbladder may be contracted. Even in these situations, gallstones may be identified. Also, the gallbladder may be in a permanent state of contraction in cases of chronic cholecystitis. In these situations the wall, echo, and shadow, or “WES,” triad is observed. This corresponds to a visualization of the anterior gallbladder wall, with echogenicity representing the echogenic gallstones and posterior acoustic shadowing ( Fig. 17.5 ). Again, this WES triad is fairly specific for chronic cholecystitis and cholelithiasis, but in patients with gallstones who are not fasting, their gallbladder may have a similar appearance. “Twinkle” artifact can also be seen in this entity . Patients with porcelain gallbladders will have an echogenic gallbladder wall with some shadowing. A porcelain gallbladder may predispose a patient to gallbladder cancer.

موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 7:39 pm

Fig. 17.1
Diagram demonstrating normal anatomy of the upper abdomen, including the relationship of the hepatic artery to the common bile duct and the biliary ductal system.
Redrawn with permission from Soni NJ. Point of Care Ultrasound . Philadelphia, PA: Elsevier; 2015:146, Fig. 19.2
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Fig. 17.2
Cholelithiasis/focal fatty sparing of the liver. Scans through the gallbladder demonstrated multiple echogenic foci ( curved arrow ) with acoustic shadowing ( arrowheads ), which are consistent with gallstones. In addition, there is a focal hypoechoic region noted anterior to the gallbladder ( arrows ), which represents an area of focal fatty sparing in a patient with diffuse fatty infiltration of the liver.
From McGahan J. General and Vascular Ultrasound: Case Review . 3rd ed. Philadelphia, PA: Elsevier; 2016:117, Fig. 57-1.
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Fig. 17.3 Gallstone with “twinkle” artifact. (A) Large gallstone ( calipers ) in a contracted gallbladder. (B) Color Doppler demonstrates mosaic appearance to the color originating at the anterior surface of the gallbladder, representing the “twinkle” artifact
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Fig. 17.4
Bowel mimicking gallstones. (A) This longitudinal scan of the liver and gallbladder demonstrates an echogenic focus ( curved arrow ) noted anteriorly within the gallbladder with distal acoustic shadowing ( arrows ). (B) Another scan, using different probe angulation, demonstrates the echogenic focus. This was bowel that moved, and there was no evidence of cholelithiasis.
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Fig. 17.5
Wall echo shadow (WES) triad. (A) Transverse image demonstrating anterior gallbladder wall ( curved arrow ) and partially collapsed gallbladder surrounding a large gallstone ( arrow ). Posterior to this there is an echogenic focus with acoustic shadowing ( arrow heads ) representing a large gallstone. There is still some fluid within the gallbladder. (B) In another patient, there is a near completely contracted gallbladder with anterior gallbladder wall ( W ) surrounding the gallstone as an echogenicity ( E ) and distal acoustic shadowing ( S ), giving the WES appearance.
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Fig. 17.6
Biliary sludge and cholelithiasis. (A) To the left side of the image there is an echogenic mass ( arrow ) without shadowing within the gallbladder lumen representing gallbladder sludge. To the right, there are multiple echogenic foci ( curved arrows ) with acoustic shadowing, representing gallstones. (B) When the patient is placed in an upright position, this mass ( arrow ) is mobile and falls to the dependent portion of the gallbladder. Note: Multiple echogenicities ( curved arrow ) within this echogenic sludge represent the gallstones.

موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 7:44 pm

TABLE 17.2
Cholelithiasis and Possible Mimics

[th]Cause[/th][th]Finding[/th]

Multiple stones	Echogenic layer with acoustic shadowing.
Sludge/sludgeball	Usually dependent, no color. Often mobile.
Stones and sludge	Stones surrounded by sludge (as above).
Blood	Dependent in gallbladder /or fills entire gallbladder. No shadowing.
Pus	Similar to blood, but with finding of acute cholecystitis.
Pseudo-sludge	A curvilinear echogenicity whose borders may project beyond the gallbladder and may disappear with different transducer orientations.
Parasites	Only in endemic areas or in patients from these areas.
Gallbladder polyps	Small masses with or without color flow.
Gallbladder cancer	Gallbladder mass with color flow and wall thickening, and often gallstones.

موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 7:52 pm

Gallbladder Masses: Polyps

Both benign and malignant gallbladder masses may be encountered when examining the gallbladder in the acute setting. This includes gallbladder polyps, cancer, or, rarely, metastasis ( Fig. 17.7) ,

. Most polyps are small and may resolve spontaneously. However, adenomatous polyps may be precancerous.

Fig. 17.7
Gallbladder polyps. (A) This image demonstrates an echogenic focus without shadowing ( calipers ) in the dependent portion of the gallbladder, representing a gallbladder polyp. If proper technique was not used, this could be misinterpreted as a gallstone. (B) In another patient, there is an anterior echogenic focus ( arrows )
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Fig. 17.7
Gallbladder polyps. (A) This image demonstrates an echogenic focus without shadowing ( calipers ) in the dependent portion of the gallbladder, representing a gallbladder polyp. If proper technique was not used, this could be misinterpreted as a gallstone. (B) In another patient, there is an anterior echogenic focus ( arrows ) without acoustic shadowing, representing a gallbladder polyp.

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موضوع: GB cancer/adenomyomatosis السبت يونيو 29, 2024 8:00 pm

Gallbladder Cancer

Gallbladder cancer may be missed on routine ultrasound. This is probably due to the fact that gallstones are often present in patients with gallbladder cancer, and any mass within the gallbladder may be obscured by the gallstones. Gallbladder carcinoma can be echogenic, isoechoic, or hypoechoic, and usually does have color Doppler flow. Gallbladder cancer may cause either diffuse or focal thickening of the gallbladder wall ( Fig. 17.8 ). Primary gallbladder cancer may invade the adjacent liver. Various cancers, including melanoma and gastrointestinal (GI) cancers, may metastasize to the gallbladder and appear as a vascular gallbladder mass.

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Fig. 17.8
Gallbladder carcinoma. Longitudinal scan of the gallbladder demonstrates a gallstone ( curved arrow ) with a nonmobile mass ( arrow ) in the gallbladder. There is also gallbladder wall thickening. An ill-defined mass ( arrowheads ) in the liver represents local invasion into the liver from the gallbladder adenocarcinoma.

Adenomyomatosis

Adenomyomatosis is characterized by epithelial proliferation and mucosal diverticula called Rokitansky–Aschoff sinuses. The most common form creates localized and confined wall thickening at the fundus of the gallbladder. This thickening can be so great, it appears as a mass and may be hard to distinguish from gallbladder cancer. There are other rare forms of segmental or diffuse adenomyomatosis. The pathognomonic finding of adenomyomatosis is the presence of hyperechoic foci, most commonly noted in the anterior wall of the gallbladder, which produces a comet tail artifact that decreases in width and amplitude more posteriorly ( Fig. 17.9 ,). This is thought to be secondary to cholesterol crystals within the Rokitansky–Aschoff sinuses in the gallbladder wall. Color Doppler will show a “twinkle artifact” in this entity (see Fig. 17.9 ), which is similar to the “twinkle” artifact seen with gallstones.

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Fig. 17.9
Adenomyomatosis. (A) Transverse scan through the gallbladder demonstrates a few echogenic foci with “ring-down artifact” ( arrow ). Note this is different than in cholelithiasis, where there is acoustic shadowing. (B) In the same region there is “twinkle” artifact ( arrow ), which can be seen with both adenomyomatosis and cholelithiasis.
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موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 8:03 pm

Acute Right Upper Quadrant Pain

The American College of Radiology has imaging criteria for patients with right upper quadrant pain who have fever, leukocytosis, and a clinical positive Murphy’s sign, and recommends ultrasound as the first-line test in these situations ( Table 17.3 ). Patients may present with acute or chronic pain in the right upper quadrant of the abdomen. The level and acuity of pain are secondary to the etiology of the pain. For instance, chronic pain may be secondary to chronic cholecystitis and cholelithiasis, whereas more acute pain may be secondary to acute cholecystitis, gallbladder perforation, or acute biliary obstruction. Abnormalities of the liver, biliary tract, pancreas, or kidney should be considered in the differential as listed in Table 17.4 . In some situations, the etiology of the pain may not be discovered or may be secondary to etiologies that may require other imaging, such as CT.

TABLE 17.3
Imaging Criteria Patients with Fever, Elevated White Blood Cell Count, Positive Murphy’s Sign
From Yarmish GM, Smith MP, Rosen MP, et al. ACR appropriateness criteria right upper quadrant pain. J Am Coll Radiol . 2014;11 3 :316–322.
[th]Radiologic Procedure[/th][th]Rating[/th][th]Comments[/th][th]Relative Radiation Level[/th]

Ultrasound abdomen	9		○
MRI abdomen without and with contrast	6	Based on ultrasound findings, this generally should follow an ultrasound of the right upper quadrant.	○
Cholescintigraphy	6
CT abdomen with contrast	6
MRI abdomen without contrast	4		○
CT abdomen without contrast	4
CT abdomen without and with contrast	3

Note: Rating scale: 1, 2, and 3 = usually not appropriate; 4, 5, and 6 = may be
appropriate; 7, 8, and 9 = usually appropriate

موضوع: رد: GB & BILIARY US السبت يونيو 29, 2024 8:13 pm

TABLE 17.4
Potential Etiologies of Right Upper Quadrant Pain, Including Those Due to Gallbladder Disease, Biliary Disease, or Disease in Surrounding Organs
    Cholelithiasis
    Acute calculus cholecystitis
    Acute acalculous cholecystitis
    Complications of acute cholecystitis
    Biliary obstruction
    Pancreatic mass (see Chapter 18 )
    Pancreatitis (see Chapter 18 )
    Hepatitis, hepatic abscess/mass (see Chapter 16 )
    Pyelonephritis or renal obstruction (see Chapter 19 )
    Renal colic/abscess (see Chapter 19 )
    Gastroenteritis/colon disease
    Abdominal aortic aneurysm
    Right lower lobe pneumonia
    No identified etiology

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