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موقع د. كمال سيد الدراوي
RADIOPEDIA  ARTICLES 356



اهلا وسهلا بك زائرنا الكريم علي صفحات منتدانا

( دكتور كمال سيد الدراوي)

عزيزي الزائر الكريم .. زيارتك لنا أسعدتنا كثيراً

ونتمني لك اطيب وانفع الاوقات علي صفحات منتدانا
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RADIOPEDIA.ORG
https://radiopaedia.org/articles/early-pregnancy?lang=gb



MD radiology sudan medical specialization board
SMSB
dr Tarteel kamal sayed

RADIOPEDIA

[rtl]https://radiopaedia.org[/rtl]

RADIOPEDIA ARTICLES
https://radiopaedia.org/articles/11-13-week-antenatal-scan?lang=gb

11-13 w11-13 week antenatal scan is considered a routine investigation advised for the fetal well being as well as 
(for early screening in pregnancy (see antenatal screening 
It includes multiple components and is highly dependant on the operator. Traditionally three factors are used to calculate the risk of trisomies:
(crown rump length (must be 45 to 84 mm, gestation age 11 weeks 3 days to 13 weeks 6 days* 
nuchal translucency*
fetal heart rate*
Additional markers increase the detection rate and reduce the false positive rates:
nasal bone
ductus venosus flow
tricuspid flow
Combining these factors with blood tests (i.e. dual marker) has been reported to achieve nearly 95% detection rate for trisomies.
Apart from the screening protocol, early detection of major anomalies may be possible and the checklist must include the following conditions:
acrania
encephalocele
alobar holoprosencephaly
iniencephaly
body stalk deformity
gastroschisis
omphalocele
limb reduction
megacystis
Quiz questions
Which of the following statement is false regarding 11-13 weeks antenatal scan?
fetal urinary bladder length more than 7 mm increases the risk of trisomy 13/18
none
presence of atrioventricular septal defect increases the risk of trisomy 21
presence of diaphragmatic hernia increases the risk of trisomy 18
presence of holoprosencephaly increases the risk of trisomy 13
with CRL more than 55 mm, if omphalocele is present, it increases the risk of trisomy 13 to 1:10 and trisomy 18 to 1:4 regardless of any other finding.
ANS : none
Explanation
All of the statements are true regarding 11-13 weeks antenatal scan 
with CRL <55 mm, omphalocele containing only bowel is not taken into risk calculation for trisomies as this may be physiological herniation, however, if there is liver in the herniated contents, it will increase the risk even with CRL <55 mm
fetal urinary bladder length between 7-15 mm increases the risk of trisomy 13/18 more as compared to the length greater than 15 mm
a diaphragmatic hernia increases the risk of trisomy 18 to 1:4
atrioventricular septal defect increases the risk of trisomy 21 to 1:2
holoprosencephaly increases the risk of trisomy 13 to 1:2
next Q





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Early pregnancy
Early pregnancy roughly spans the first ten weeks of the first trimester.

https://radiopaedia.org/articles/early-pregnancy?lang=gb

 
Radiographic features
Antenatal ultrasound 

zero - 4.3 weeks: no ultrasound findings 

w4.3 - 5 weeks
possible small gestational sac
(possible double decidual sac sign (DDSS 
(possible intradecidual sac sign (IDSS 

5.1-5.5 weeks:
​gestational sac should be visible by this time

5.5-6.0 weeks 
yolk sac should be visible by this time
gestational sac should be ~6 mm in diameter
double bleb sign

more than 6 wks 
(fetal pole may be identifiable on endovaginal ultrasound (1-2 mm 
fetal heart rate (FHR) should be ~100-115 bpm
gestational sac should be ~10 mm in diameter

6.5 weeks
crown rump length (CRL) should be ~5 mm

7-8 weeks
CRL is between 11-16 mm
cephalad and caudal poles can be identified

8-9 weeks
CRL is between 17-23 mm
limb buds appear
head can be seen as separate from the body

9-10 weeks
CRL is between 23-32 mm
fetal heart rate 170-180 bpm
fetal movement can be seen
a round hypoechoic structure in the fetal brain represents a developing embryonic/fetal rhombencephalon
nuchal translucency may begin to be seen
Transvaginal/endovaginal (TV/EV) scanning
intradecidual sac sign (IDSS): early sign on a TV scan
when the MSD measures 25 mm, an embryo must be visible
when the CRL measures >7 mm, an embryo must show cardiac activity
an embryo should be seen <=14 days after a scan with a gestational sac without a yolk sac
an embryo should be seen <=11 days after a scan with a gestational sac and a yolk sac
Transabdominal (TA) scanning
when the MSD measures 20 mm a yolk sac should be visible
when the MSD measures 25 mm, an embryo must be visible
CT/MRI
Occasionally, early pregnancy is unintentionally imaged by CT or sometimes MRI is done for some concurrent pathology, and its important to know the imaging findings 3.

fluid-filled cystic structure in endometrial cavity (well identified on MRI, and may be visible on CT especially on delayed post-contrast images)
developing placenta seen as curvilinear enhancing structure
fetal pole may be seen in delayed first trimester imaging
corpus luteal cyst may be visible in one of the ovaries
unilocular <3 cm cyst with irregular crenated and enhancing walls

Differential diagnosis to be considered with a positive urinary pregnancy test includes
ectopic pregnancy
missed abortion
gestational trophoblastic disease
If urinary pregnancy test is negative similar findings may suggest submucosal fibroid or retained products of conception.

Practical points
The earlier in pregnancy a scan is performed, the more accurate the age assignment from crown rump length. The initial age assignment should not be revised on subsequent scans 5.

(Overall, the accuracy of sonographic dating in the first trimester is ~5 days (95% confidence range



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First trimester of pregnancy

first trimester
ultrasound findings in early pregnancy
gestational sac
(mean sac diameter (MSD 
yolk sac
fetal pole
(crown rump length (CRL 
confirming intrauterine gestation
double decidual sac sign
intradecidual sign
double bleb sign
(pregnancy of unknown location (PUL 
first trimester vaginal bleeding
ectopic pregnancy
pseudogestational sac
decidual cast
tubal ectopic
ampullary
isthmal 
fimbrial
atypical ectopic pregnancies
interstitial ectopic 
eccentric gestational sac
interstitial line sign
ovarian ectopic 
cervical ectopic
scar ectopic
abdominal ectopic
live ectopic pregnancy
heterotopic pregnancy
tubal rupture 
failed early pregnancy
(pregnancy of uncertain viability (PUV 
miscarriage
threatened miscarriage
irregular gestational sac
missed miscarriage
inevitable miscarriage
incomplete miscarriage
complete miscarriage
anembryonic pregnancy
anembryonic pregnancy in the exam
yolk sac abnormalities
irregular yolk sac
calcified yolk sac
echogenic yolk sac
small yolk sac
large yolk sac
gestational trophoblastic disease
subchorionic haemorrhage
demise of a twin
implantation bleeding
aneuploidy testing
antenatal screening
11-13 weeks antenatal scan
nuchal translucency



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Eleven ribs or less is associated with a number of congenital abnormalities and skeletal dysplasias, including:

Down syndrome, Trisomy 21
campomelic dysplasia
kyphomelic dysplasias
(asphyxiating thoracic dysplasia (Jeune syndrome 
short rib polydactyly syndromes
trisomy 18
chromosome 1q21.1 deletion syndrome​
atelosteogenesis
spondylocostal dysostosis
spondylometaphyseal dysplasia, Sedaghatain type
Ritscher-Schinzel syndrome

*******

1.5Tesla vs 3.0 T
Comparing 1.5 T vs 3.0 T (1.5 tesla vs 3.0 tesla) MRI systems identifies a number of differences; 
a 3 T system has

(increased signal-to-noise ratio (SNR 
increased spatial resolution
increased temporal resolution
(increased specific absorption rate (SAR 
increased acoustic noise

Signal-to-noise ratio
Theoretically, signal is proportional to the square of the static field strength (B0) whereas noise increases linearly. This implies that, in a perfect system, the signal-to-noise ratio (SNR) of a 3 T system would be twice as good as at 1.5 T. In reality, due to an increase in susceptibility effects in most tissues, the actual improvement is only in the 30-60% range (instead of 100%). With this increased SNR, the spatial resolution and/or acquisition time can be improved, depending on which is more important for the particular case.

Specific absorption rate
Specific absorption rate (SAR) is defined as the amount of radiofrequency energy (joules) deposited in tissues (kg). The limit set by the FDA is an amount which results in an increase of 1-degree centigrade in any tissue 2. SAR is proportional to the static field (B0) squared, meaning that a 3 T system deposits 4 times as much energy within tissue as a 1.5 T system. Additionally, SAR is proportional to

pulse duration and length
pulse number
slice number
flip angle
The dependence of SAR on flip angle results in a relatively large amount of energy deposition for standard spin echo sequences since they use 90-degree flip angles. As a result, there is increased use of gradient echo sequences, which use smaller flip angles. Unfortunately, these latter sequences image T2* and not T2, and are therefore more susceptible to local field artefacts. These problems have largely been overcome with modern units.

Acoustic noise
Rapid gradient switching leads to an increase in the intensity of the acoustic noise, which requires better insulation of both the unit itself and the containing room.

Quiz questions
Changing from a 1.5 Tesla to a 3 Tesla MRI system will:

increase spatial resolution, increase signal-to-noise ratio and decrease temporal resolution
increase spatial resolution, decrease signal-to-noise ratio and decrease temporal resoution
increase spatial resolution, increase signal-to-noise ratio and increase temporal resolution
decrease spatial resolution, increase signal-to-noise ratio and decrease temporal resolution
decrease spatial resolution, decrease signal-to-noise ratio and decrease temporal resoution

[rtl]https://radiopaedia.org/articles/15-t-vs-30-t?lang=gb[/rtl]

Explanation
see [rtl]https://radiopaedia.org/articles/15t-vs-3t[/rtl]



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